Monroe County, TN (WOKI) The Tennessee Bureau of Investigation is investigating a deadly house fire Tuesday morning in Monroe County.

Officials with the Madisonville Police Department say the fire broke out around 5:00 a.m. in the 500 block of Old Cemetery Road, and there were reports of people possibly trapped inside.

MPD says when officers arrived on the scene, the home was engulfed in flames and that two adults and a child had escaped the residence, but two other adults and a child were still unaccounted for within the burning home.

According to MPD, officers and firefighters with the Madisonville Fire Department tried to rescue those trapped inside, but the flames were too intense for emergency crews to reach them.

“Our heartfelt condolences and prayers go out to the families affected by this heart-wrenching tragedy, not just today but in the difficult days ahead,” MPD said.

“We also wish to express our gratitude to the Madisonville Fire Department, Monroe County EMS, Monroe County E-911, Tennessee Bureau of Investigation, 10th District Attorney General’s Office, Sweetwater Police Department, and Monroe County Rescue Squad for their support and assistance during this investigation,” MPD continued.

The Tennessee Bureau of Investigation is leading the investigation into the fire.

Additional information, including the identities of those who died, has not been released.